Colon Adenocarcinoma

A 70 year old man experienced bright red blood per rectum and was found to have iron deficiency anemia. He underwent colonoscopy that revealed a large, fungating, friable mass in the sigmoid colon. The patient underwent a sigmoid colectomy.

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Questions

  1. What are the histological characteristics of this mass?
  2. What is the diagnosis?
  3. What is the relationship of this lesion to the one seen inslide 4 (Adenoma)? See description of morphologic and molecular changes.

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